| Rank | Player | Att | RuYard | RuTD | Target | Rec | ReYard | ReTD | FPTS |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
Christian McCaffreyC. McCaffrey
SF - RB |
271 | 1261 | 10 | 86 | 68 | 568 | 5 | 341 |
| 2 |
CeeDee LambC. Lamb
DAL - WR |
12 | 87 | 0 | 159 | 117 | 1604 | 9 | 338 |
| 3 |
Breece HallB. Hall
NYJ - RB |
229 | 1074 | 7 | 96 | 75 | 577 | 5 | 312 |
| 4 |
Tyreek HillT. Hill
MIA - WR |
5 | 22 | 0 | 159 | 111 | 1410 | 8 | 304 |
| 5 |
Justin JeffersonJ. Jefferson
MIN - WR |
1 | 3 | 0 | 154 | 106 | 1462 | 7 | 297 |
| 6 |
Amon-Ra St. BrownA. St. Brown
DET - WR |
4 | 32 | 0 | 160 | 106 | 1374 | 8 | 295 |
| 7 |
Ja'Marr ChaseJ. Chase
CIN - WR |
1 | 10 | 0 | 150 | 97 | 1327 | 9 | 285 |
| 8 |
Bijan RobinsonB. Robinson
ATL - RB |
202 | 1005 | 5 | 96 | 67 | 538 | 6 | 285 |
| 9 |
Puka NacuaP. Nacua
LAR - WR |
11 | 80 | 0 | 136 | 99 | 1408 | 6 | 284 |
| 10 |
Saquon BarkleyS. Barkley
PHI - RB |
269 | 1078 | 11 | 70 | 49 | 352 | 4 | 282 |
| 11 |
Davante AdamsD. Adams
LV - WR |
0 | 0 | 0 | 150 | 96 | 1206 | 7 | 261 |
| 12 |
Garrett WilsonG. Wilson
NYJ - WR |
1 | 12 | 0 | 165 | 90 | 1236 | 7 | 257 |
| 13 |
A.J. BrownA. Brown
PHI - WR |
0 | 0 | 0 | 140 | 86 | 1310 | 7 | 257 |
| 14 |
Alvin KamaraA. Kamara
NO - RB |
199 | 791 | 6 | 98 | 76 | 544 | 1 | 254 |
| 15 |
Derrick HenryD. Henry
BAL - RB |
271 | 1255 | 11 | 33 | 27 | 222 | 2 | 253 |
| 16 |
Chris OlaveC. Olave
NO - WR |
0 | 0 | 0 | 130 | 90 | 1229 | 6 | 251 |
| 17 |
Mike EvansM. Evans
TB - WR |
0 | 0 | 0 | 122 | 78 | 1157 | 9 | 248 |
| 18 |
Kyren WilliamsK. Williams
LAR - RB |
263 | 1123 | 11 | 54 | 33 | 257 | 2 | 247 |
| 19 |
Marvin Harrison Jr.M. Harrison Jr.
ARI - WR |
1 | 5 | 0 | 130 | 91 | 1211 | 6 | 247 |
| 20 |
Jonathan TaylorJ. Taylor
IND - RB |
267 | 1159 | 10 | 41 | 34 | 295 | 1 | 245 |
